Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 8/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949183 | 0.90 | HTR2C (0.57) | HTR2AHTR3AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL16660426 | 0.82 | HTR3A (0.59) | HTR2AHTR3ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL724585 | 0.82 | HTR3A (0.59) | HTR2AHTR3ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28294833 | 0.81 | KDM1A (0.43) | HTR2AHTR2CNOTUM | |
| SCHEMBL18161909 | 0.81 | KDM1A (0.43) | HTR2AHTR2CNOTUM | |
| SCHEMBL4882952 | 0.80 | P2RY14 (0.42) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL4882966 | 0.80 | P2RY14 (0.42) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL4882961 | 0.80 | P2RY14 (0.42) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL16878949 | 0.80 | AR (0.56) | HTR2AHTR3AHTR2C | |
| Hydrochloric Acid SCHEMBL16879319 | 0.79 | AR (0.55) | HTR2AHTR3AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233978-A1 | Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders | OTSUKA AMERICA PHARMACEUTICAL, INC. | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233978-A1 | Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders | HTR3C, HTR1B, HTR2C | HTR2A 20/4885HTR3A 10/4885HTR2C 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.