Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698358 | 0.81 | AGPAT2 (0.42) | KMT2AHSD17B1POLBMAPTLMNA | |
| SCHEMBL4167912 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL850628 | 0.76 | ALDH1A1 (0.46) | ALDH1A1PDK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10885379 | 0.76 | S100B (0.50) | ALDH1A1PDK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14426576 | 0.76 | GPBAR1 (0.48) | ALDH1A1PDK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9839331 | 0.75 | DHODH (0.41) | ALDH1A1RAB9ANPC1KMT2AHSD17B1 | |
| SCHEMBL9796263 | 0.74 | POLB (0.49) | ALDH1A1PDK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13553363 | 0.74 | ALDH1A1 (0.44) | ALDH1A1PDK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14341655 | 0.73 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL10048011 | 0.73 | ALDH1A1 (0.50) | ALDH1A1PDK2SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238768-A1 | MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS | AXELSSON OSKAR | 2009-09-24 | — | — | US | disclosed |
| US-20090238768-A1 | MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS | AXELSSON OSKAR | 2009-09-24 | — | — | US | disclosed |
| WO-2007064227-A1 | MULTIMERIC MAGENTIC RESONANCE CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238768-A1 | MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS | MAG, MSR1, FABP7 | ALDH1A1 2448/4885PDK2 2423/4885SMN1; SMN2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.