Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769004 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SLC18A3DRD2DRD3 | |
| SCHEMBL13698452 | 0.79 | DRD2 (0.59) | ALDH1A1SLC18A3DRD2DRD3 | |
| SCHEMBL13698537 | 0.73 | SLC18A3 (0.65) | ALDH1A1SLC18A3DRD2DRD3KDM4E | |
| SCHEMBL13698556 | 0.73 | HTR3E (0.57) | ALDH1A1SLC18A3DRD2KDM4E | |
| SCHEMBL2544985 | 0.72 | SLC18A3 (0.54) | ALDH1A1SLC18A3DRD2DRD3 | |
| SCHEMBL3165674 | 0.72 | DRD2 (0.72) | ALDH1A1DRD2DRD3 | |
| SCHEMBL30407688 | 0.72 | DRD2 (0.72) | ALDH1A1DRD2DRD3KDM4E | |
| SCHEMBL27645131 | 0.71 | DRD2 (0.62) | ALDH1A1SLC18A3DRD2DRD3 | |
| SCHEMBL1374764 | 0.71 | DRD2 (0.71) | ALDH1A1DRD2DRD3KDM4E | |
| SCHEMBL14529139 | 0.71 | ALDH1A1 (0.64) | ALDH1A1SLC18A3DRD2DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239873-A1 | Phenyl-piperazine derivatives as modulators of muscarinic receptors | BLANCO MIGUEL GARCIA-GUZMAN | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239873-A1 | Phenyl-piperazine derivatives as modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | ALDH1A1 2270/4885SLC18A3 187/4885DRD2 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.