⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821399 | 0.71 | HDAC4 (0.41) | — | |
| SCHEMBL20743619 | 0.67 | LOXL2 (0.43) | — | |
| SCHEMBL22609293 | 0.66 | LOXL2 (0.48) | — | |
| SCHEMBL18248463 | 0.66 | CYP11B2 (0.38) | — | |
| SCHEMBL29770233 | 0.63 | S1PR1 (0.43) | — | |
| SCHEMBL4926043 | 0.63 | S1PR1 (0.43) | — | |
| SCHEMBL276906 | 0.62 | — | — | |
| SCHEMBL22322736 | 0.62 | — | — | |
| SCHEMBL883790 | 0.62 | — | — | |
| SCHEMBL2012248 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109642-A1 | USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR | 常州大学 | 2024-05-30 | — | — | WO | disclosed |
| US-20230363268-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-11-09 | — | — | US | disclosed |
| CN-116874432-A | As beta 2 Benzimidazole derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-10-13 | — | — | CN | disclosed |
| US-20230069900-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-03-09 | — | — | US | disclosed |
| CN-107382969-B | Phenylpyrazole zwitterionic compound and application thereof in resistant pest control | 华南农业大学 | 2020-08-07 | — | — | CN | disclosed |
| CN-109195946-A | Carbamate derivatives compound, preparation method and the usage | 生物药品解决方案有限公司 | 2019-01-11 | — | — | CN | disclosed |
| EP-2411001-B1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME (US) | 2018-01-17 | — | — | EP | disclosed |
| US-20170217972-A1 | 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-03 | — | — | US | disclosed |
| US-20170217972-A1 | 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-03 | — | — | US | disclosed |
| US-8815854-B2 | Substituted imidazopyridinyl compounds | ARQULE, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815854-B2 | Substituted imidazopyridinyl compounds | ARQULE, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2012177852-A1 | SUBSTITUTED IMIDAZOPYRIDINYL COMPOUNDS | ARQULE, INC (US) | 2012-12-27 | — | — | WO | disclosed |
| US-20120329793-A1 | Substituted Imidazopyridinyl Compounds | ARQULE, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329793-A1 | Substituted Imidazopyridinyl Compounds | ARQULE, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2096108-A1 | Novel organic electroluminescent compounds and organic electroluminscent device using the same | Gracel Display Inc. (KR) | 2009-09-02 | — | — | EP | disclosed |