Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772471 | 0.79 | LOXL2 (0.48) | LOXL2CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL1985814 | 0.78 | CALM1 (0.55) | LOXL2CYP11B1CYP11B2HSD17B10TAAR1 | |
| SCHEMBL7482733 | 0.78 | CYP17A1 (0.58) | CYP11B1CYP11B2CYP17A1CYP3A4ALDH1A1 | |
| SCHEMBL16561361 | 0.76 | IDO1 (0.58) | LOXL2CYP3A4IDO1TAAR1ALDH1A1 | |
| SCHEMBL1468357 | 0.76 | IDO1 (0.58) | LOXL2CYP3A4IDO1TAAR1ALDH1A1 | |
| SCHEMBL28302304 | 0.75 | LTA4H (0.55) | LOXL2CYP11B1CYP11B2CYP17A1IDO1 | |
| Hydrochloric Acid SCHEMBL7941845 | 0.74 | IDO1 (0.55) | LOXL2CYP3A4IDO1TAAR1ALDH1A1 | |
| SCHEMBL3758352 | 0.73 | TBXAS1 (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL18770326 | 0.72 | CYP17A1 (0.68) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL28566929 | 0.72 | LOXL2 (0.41) | LOXL2CYP3A4HSD17B10ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | LOXL2 227/4885CYP11B1 278/4885CYP11B2 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.