Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699131 | 1.00 | APP (0.41) | APPGPR84SOD1KDM4EALOX15 | |
| SCHEMBL13699327 | 0.89 | APP (0.40) | APPGPR84KDM4EALOX15MEN1 | |
| SCHEMBL1898008 | 0.89 | GPR84 (0.45) | GPR84SOD1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL5320737 | 0.82 | APP (0.53) | APPMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL8955457 | 0.80 | PDK2 (0.43) | GPR84SOD1ALOX15MAPK1RHOC | |
| SCHEMBL15519689 | 0.80 | PDK2 (0.43) | GPR84SOD1ALOX15MAPK1RHOC | |
| SCHEMBL9248280 | 0.80 | PDK2 (0.43) | GPR84SOD1ALOX15MAPK1RHOC | |
| SCHEMBL14589427 | 0.78 | GPR84 (0.39) | GPR84SOD1KDM4EALOX15MAPK1 | |
| SCHEMBL16493151 | 0.77 | NOTUM (0.41) | GPR84SOD1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL13699127 | 0.77 | TP53 (0.44) | GPR84SOD1ALOX15ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113704-A2 | FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME | KYOTO UNIVERSITY (JP) | 2009-09-17 | — | — | WO | disclosed |