Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604600 | 0.89 | APP (0.53) | APPCYP3A4SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL584253 | 0.89 | CYP3A4 (0.58) | CYP3A4SMN1; SMN2ALDH1A1LTA4HNOS1 | |
| SCHEMBL12676015 | 0.85 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2ALDH1A1LTA4HNOS1 | |
| SCHEMBL24303208 | 0.84 | APP (0.67) | APPCYP3A4SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3085759 | 0.84 | APP (0.67) | APPCYP3A4SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7747383 | 0.84 | LTA4H (0.58) | CYP3A4SMN1; SMN2ALDH1A1LTA4HNOS1 | |
| SCHEMBL225915 | 0.83 | NOS1 (0.50) | CYP3A4SMN1; SMN2ALDH1A1LTA4HNOS1 | |
| SCHEMBL466232 | 0.82 | APP (0.65) | APPCYP3A4SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5457352 | 0.82 | SMN1; SMN2 (0.56) | APPCYP3A4SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL970017 | 0.82 | SMN1; SMN2 (0.56) | APPCYP3A4SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440251-B | Method for photo/nickel concerted catalysis of monoarylation diol | 陕西师范大学 | 2021-01-01 | — | — | CN | disclosed |
| WO-2007089455-A1 | FLUOROALKENYL DERIVATIVES AS INSECTICIDES AND NEMATICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |