SCHEMBL13699127

SCHEMBL13699127

Cc1cc(OCCO)cc(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
CYP3A4 P08684 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SCN9A Q15858 4/20 0.39
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
RXRG P48443 2/20 0.39
GPR84 Q9NQS5 1/20 0.38
ALDH1A1 P00352 1/20 0.37
RECQL P46063 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GPBAR1 Q8TDU6 1/20 0.36
SOD1 P00441 1/20 0.36
PDK2 Q15119 1/20 0.35
SRC P12931 1/20 0.35
ZAP70 P43403 1/20 0.35
SYK P43405 1/20 0.35
NR1I2 O75469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699327 0.91 APP (0.40) TP53ALOX15CYP3A4SMN1; SMN2SCN9A
SCHEMBL1898008 0.87 GPR84 (0.45) CYP3A4SMN1; SMN2SCN9ARXRARXRB
SCHEMBL19904783 0.83 KDM4E (0.42) SCN9AGPR84ALDH1A1L3MBTL1GPBAR1
SCHEMBL16961046 0.83 FAAH (0.42) TP53ALOX15SCN9AGPR84L3MBTL1
SCHEMBL10359827 0.81 TP53 (0.59) TP53ALOX15CYP3A4SMN1; SMN2ALDH1A1
SCHEMBL16729641 0.80 MAPT (0.50) ALOX15SMN1; SMN2RXRARXRBRXRG
SCHEMBL13180038 0.80 RXRA (0.48) RXRARXRBRXRGALDH1A1L3MBTL1
SCHEMBL10104419 0.80 MAPT (0.49) ALDH1A1PDK2
SCHEMBL26070114 0.80 PLA2G2A (0.44) TP53ALOX15L3MBTL1PDK2
SCHEMBL16493151 0.79 NOTUM (0.41) CYP3A4SMN1; SMN2SCN9ARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009113704-A2 FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME KYOTO UNIVERSITY (JP) 2009-09-17 WO disclosed