SCHEMBL13699129

SCHEMBL13699129

CC(C)(C)OC(=O)NCCCCCNC(=O)c1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.50
CA2 P00918 8/20 0.50
CA12 O43570 4/20 0.49
CA9 Q16790 4/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
RAB9A P51151 1/20 0.45
TP53BP1 Q12888 3/20 0.44
DRD2 P14416 1/20 0.44
STAT3 P40763 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284884 0.87 SMN1; SMN2 (0.59) CA1CA2CA12CA9TDP1
SCHEMBL16152246 0.83 SMN1; SMN2 (0.60) CA1CA2CA12CA9MEN1
SCHEMBL31432149 0.82 NAMPT (0.55) CA1CA2CA12CA9TDP1
SCHEMBL14679384 0.81 NPC1 (0.54) MEN1KMT2ATDP1SMN1; SMN2RAB9A
SCHEMBL30131142 0.81 CA1 (0.61) CA1CA2CA12CA9
SCHEMBL17038712 0.80 CA1 (0.44) CA1CA2CA12CA9MEN1
SCHEMBL284764 0.80 SMN1; SMN2 (0.55) MEN1KMT2ASMN1; SMN2TP53BP1
SCHEMBL34475125 0.79 CA2 (0.55) CA1CA2CA12CA9
SCHEMBL16151786 0.78 SMN1; SMN2 (0.71) CA1CA2KMT2ATDP1SMN1; SMN2
SCHEMBL14679385 0.78 NPC1 (0.54) MEN1KMT2ASMN1; SMN2RAB9ATP53BP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009113704-A2 FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME KYOTO UNIVERSITY (JP) 2009-09-17 WO disclosed