Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284884 | 0.96 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53BP1TDP1CA1CA2 | |
| SCHEMBL16151786 | 0.95 | SMN1; SMN2 (0.71) | SMN1; SMN2TP53BP1TDP1CA1CA2 | |
| SCHEMBL284764 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53BP1KMT2AMEN1GAA | |
| SCHEMBL14679385 | 0.92 | NPC1 (0.54) | SMN1; SMN2TP53BP1KMT2AMEN1GAA | |
| SCHEMBL22767691 | 0.91 | TDP1 (0.56) | SMN1; SMN2TDP1CA1CA2KMT2A | |
| SCHEMBL31407324 | 0.91 | TP53BP1 (0.70) | SMN1; SMN2TP53BP1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1467340 | 0.90 | NAAA (0.56) | SMN1; SMN2TDP1KMT2AMEN1GAA | |
| SCHEMBL14679384 | 0.89 | NPC1 (0.54) | SMN1; SMN2TP53BP1TDP1KMT2AMEN1 | |
| SCHEMBL5663889 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53BP1CA1CA2KMT2A | |
| SCHEMBL264483 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53BP1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10440955-B2 | Methods comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180125070-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2018-05-10 | — | — | US | disclosed |
| US-9839219-B2 | Compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2017-12-12 | — | — | US | disclosed |
| US-20160330962-A1 | COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2016-11-17 | — | — | US | disclosed |
| US-9439433-B2 | Compositions and methods comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2016-09-13 | — | — | US | disclosed |
| US-9220267-B2 | Methods of use comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150274639-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2015-10-01 | — | — | US | disclosed |
| US-9034927-B2 | Methods of use for compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2015-05-19 | — | — | US | disclosed |
| US-20150038705-A1 | METHODS OF USE COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2015-02-05 | — | — | US | disclosed |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2015-02-05 | — | — | US | disclosed |
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH (US) | 2014-11-27 | — | — | US | disclosed |
| US-8853278-B1 | Compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2014-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | SMN1; SMN2 4707/4885TP53BP1 2042/4885TDP1 440/4885 |
| US-20150038705-A1 | METHODS OF USE COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | SMN1; SMN2 4706/4885TP53BP1 2232/4885TDP1 532/4885 |
| US-20160330962-A1 | COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMS, SMOX | SMN1; SMN2 4729/4885TP53BP1 1458/4885TDP1 367/4885 |
| US-10440955-B2 | Methods comprising a biocidal polyamine | SRM, SMOX, SMS | SMN1; SMN2 4734/4885TP53BP1 1811/4885TDP1 419/4885 |
| US-20180125070-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | SMN1; SMN2 4731/4885TP53BP1 1832/4885TDP1 450/4885 |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | SMN1; SMN2 4731/4885TP53BP1 1832/4885TDP1 450/4885 |
| US-20150274639-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | SMN1; SMN2 4707/4885TP53BP1 2042/4885TDP1 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.