Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699379 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL13699231 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL13699367 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL10523780 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL305973 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL614649 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL27492502 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL991355 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL820513 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL2849834 | 0.80 | CNR2 (0.45) | SMN1; SMN2PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |