Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820513 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL991355 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL29610080 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL9712036 | 0.94 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL7411749 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMMP8MEN1KMT2A | |
| SCHEMBL7421239 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMMP8MEN1KMT2A | |
| SCHEMBL1859511 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMMP8PIN1TDP1 | |
| SCHEMBL27496209 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTL3MBTL1TDP1PPARG | |
| SCHEMBL8888971 | 0.87 | LMNA (0.62) | L3MBTL1PPARGPPARALMNAALDH1A1 | |
| SCHEMBL9395007 | 0.87 | LMNA (0.49) | SMN1; SMN2TDP1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143620-A | Method for preparing R-2-hydroxy-4-phenylbutyric acid ethyl ester | 台州爱申特科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-115851641-A | Fusion enzyme for efficiently producing (R) -2-hydroxy-4-phenylbutyric ethyl butyrate and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115820622-A | Double-enzyme self-assembly compound and application of compound in synthesizing (R) -2-hydroxy-4-phenylbutyrate | 浙江工业大学 | 2023-03-21 | — | — | CN | claimed |
| CN-109929885-B | Method for preparing ethyl gamma-2-hydroxy-4-phenylbutyrate by coupling extraction of enzyme membrane reactor | 江苏惠利生物科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-110903177-B | Method for preparing levo muscone | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114456063-A | Method for preparing benazepril key intermediate R-2-hydroxy-4-phenylbutyric acid ethyl ester | 南方科技大学台州研究院 | 2022-05-10 | — | — | CN | claimed |
| CN-111218441-B | Magnetic immobilized yeast cell and application thereof in preparation of (R) -2-hydroxy-4-phenylbutyrate ethyl ester | 浙江工业大学 | 2022-03-18 | — | — | CN | claimed |
| CN-113584096-A | Preparation method and application of R-2-hydroxybenzene butyronitrile | 江西科苑生物股份有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-105061312-A | Improved preparation method of benazepril hydrochloride and pharmaceutical composition containing benazepril hydrochloride | HUIZHOU XINLITAI PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | claimed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| EP-1762625-B1 | Reductase gene and use thereof | SUMITOMO CHEMICAL CO (JP) | 2009-07-15 | — | — | EP | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| US-6919450-B2 | Process for the preparation of benazepril | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-19 | — | — | US | claimed |
| US-20250223263-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NodThera Limited (GB) | 2025-07-10 | — | — | US | disclosed |
| CN-119177259-B | Method for synthesizing optically active (R) -2-hydroxy-4-phenylbutyric acid by utilizing multienzyme catalysis in micro-flow field | 南京工业大学 | 2025-03-14 | — | — | CN | disclosed |
| US-5066826-A | Treating With A Base | KURARAY COMPANY, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0421472-A1 | Process for racemization of optically active 4-phenylbutanoic acid esters | KURARAY CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4525301-A | REACTING TRIFLUOROMETHANE SULFONIC ACID DERIVATIVES WITH AMINO ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250223263-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, NLRP1 | SMN1; SMN2 4362/4885MAPT 2042/4885MMP8 301/4885 |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | ACKR3, KIT, C3AR1 | SMN1; SMN2 2706/4885MAPT 4550/4885MMP8 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.