Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614649 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL820513 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL29610080 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL9712036 | 0.94 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTMMP8PIN1L3MBTL1 | |
| SCHEMBL7411749 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMMP8MEN1KMT2A | |
| SCHEMBL7421239 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMMP8MEN1KMT2A | |
| SCHEMBL1859511 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMMP8PIN1TDP1 | |
| SCHEMBL27496209 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTL3MBTL1TDP1PPARG | |
| SCHEMBL8888971 | 0.87 | LMNA (0.62) | L3MBTL1PPARGPPARALMNAALDH1A1 | |
| SCHEMBL9395007 | 0.87 | LMNA (0.49) | SMN1; SMN2TDP1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437401-B1 | Oxidoreductase | IEP GMBH (DE) | 2010-12-15 | — | — | EP | claimed |
| US-20050191735-A1 | Oxidoreductase | IEP GMBH (DE) | 2005-09-01 | — | — | US | claimed |
| WO-2011009849-A2 | METHOD FOR PREPARING OPTICALLY ACTIVE HYDROXY ACID ESTERS | BASF SE (DE) | 2011-01-27 | — | — | WO | disclosed |
| US-7575909-B2 | Oxidoreductase from pichia capsulata | IEP GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-20090131384-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090131384-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| EP-1330464-B1 | PHOSPHINO-AMINOPHOSPHINES, CATALYST COMPLEXES AND ENANTIOSELECTIVE HYDROGENATION | EASTMAN CHEM CO (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20050191735-A1 | Oxidoreductase | IEP GMBH (DE) | 2005-09-01 | — | — | US | disclosed |
| EP-1330464-A2 | PHOSPHINO-AMINOPHOSPHINES, CATALYST COMPLEXES AND ENANTIOSELECTIVE HYDROGENATION | EASTMAN CHEMICAL COMPANY (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6590115-B2 | Useful as ligands for metal catalysts for asymmetric reactions, in particular as rhodium complexes for asymmetric hydrogenation of enamide, itaconate, and alpha-ketoester compounds | EASTMAN CHEMICAL COMPANY | 2003-07-08 | — | — | US | disclosed |
| US-20020065417-A1 | Useful as ligands for metal catalysts for asymmetric reactions, in particular as rhodium complexes for asymmetric hydrogenation of enamide, itaconate, and alpha-ketoester compounds | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2002-05-30 | — | — | US | disclosed |
| WO-2002026750-A2 | PHOSPHINO-AMINOPHOSPHINES, CATALYST COMPLEXES AND ENANTIOSELECTIVE HYDROGENATION | EASTMAN CHEMICAL COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| EP-0421472-B1 | Process for racemization of optically active 4-phenylbutanoic acid esters | KURARAY CO (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5066826-A | Treating With A Base | KURARAY COMPANY, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0421472-A1 | Process for racemization of optically active 4-phenylbutanoic acid esters | KURARAY CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131384-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | NR1H3, NR1H2, SREBF1 | SMN1; SMN2 4422/4885MAPT 577/4885MMP8 3740/4885 |
| US-20020065417-A1 | Useful as ligands for metal catalysts for asymmetric reactions, in particular as rhodium complexes for asymmetric hydrogenation of enamide, itaconate, and alpha-ketoester compounds | NOTUM, WEE1, WEE2 | SMN1; SMN2 3650/4885MAPT 4067/4885MMP8 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.