Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699076 | 0.83 | CA1 (0.33) | — | |
| SCHEMBL318089 | 0.81 | KIF11 (0.41) | — | |
| SCHEMBL14208120 | 0.78 | CNR1 (0.39) | NISCH | |
| SCHEMBL18671255 | 0.77 | CYP3A4 (0.46) | — | |
| SCHEMBL3958686 | 0.75 | TUBB4A (0.45) | — | |
| SCHEMBL10102949 | 0.75 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL18986083 | 0.74 | S1PR1 (0.47) | — | |
| SCHEMBL24214987 | 0.74 | RAD52 (0.30) | — | |
| SCHEMBL10640127 | 0.74 | CBFB (0.41) | — | |
| SCHEMBL12686295 | 0.74 | GAA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589067-B2 | 6, 11-bridged tricyclic macrolides | ENANTA PHARMACEUTICALS, INC. (US) | 2009-09-15 | — | — | US | disclosed |
| WO-2007044927-A2 | 6, 11-BRIDGED TRICYCLIC MACROLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |