SCHEMBL318089

SCHEMBL318089

CCc1ccc2nn[nH]c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
ALDH1A1 P00352 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
GAA P10253 2/20 0.40
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
PTK2B Q14289 1/20 0.40
TP53 P04637 1/20 0.37
DAO P14920 1/20 0.37
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
CA12 O43570 1/20 0.35
ALPL P05186 1/20 0.35
CA9 Q16790 1/20 0.35
TYMS P04818 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208120 0.85 CNR1 (0.39) NPC1RAB9ALMNACYP1A2NPBWR1
SCHEMBL241363 0.85 TP53 (0.37) KIF11ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL27708683 0.83 TP53 (0.36) KIF11ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL6364875 0.83 TP53 (0.36) KIF11ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL3958686 0.82 TUBB4A (0.45) SMN1; SMN2NPC1RAB9AHPGDLMNA
SCHEMBL13699310 0.81 NISCH (0.32)
SCHEMBL18986083 0.81 S1PR1 (0.47) ALDH1A1LMNATP53CYP1A2KDM4E
SCHEMBL24214987 0.81 RAD52 (0.30) RAD52
SCHEMBL10640127 0.81 CBFB (0.41) ALDH1A1ALOX15
SCHEMBL12686295 0.81 GAA (0.42) GAACYP2A6NPBWR1RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12466973-B2 Packaging coating containing water-dispersible acrylic block copolymer SWIMC LLC (US) 2025-11-11 US disclosed
US-12351737-B2 Chemical mechanical polishing of substrates containing copper and ruthenium BASF SE (DE) 2025-07-08 US disclosed
EP-4491678-A2 LATEX COATING COMPOSITION HAVING REDUCED FLAVOR SCALPING PROPERTIES SWIMC LLC (US) 2025-01-15 EP disclosed
EP-4086314-B1 LATEX COATING COMPOSITION HAVING REDUCED FLAVOR SCALPING PROPERTIES SWIMC LLC (US) 2024-09-25 EP disclosed
US-20240002698-A1 CHEMICAL MECHANICAL POLISHING OF SUBSTRATES CONTAINING COPPER AND RUTHENIUM BASF SE (DE) 2024-01-04 US disclosed
US-20230416570-A1 CHEMICAL MECHANICAL POLISHING OF SUBSTRATES CONTAINING COPPER AND RUTHENIUM BASF SE (DE) 2023-12-28 US disclosed
US-11725117-B2 Chemical mechanical polishing of substrates containing copper and ruthenium BASF SE (DE) 2023-08-15 US disclosed
WO-2023064585-A1 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS VANDERBILT UNIVERSITY (US) 2023-04-20 WO disclosed
EP-4086314-A1 LATEX COATING COMPOSITION HAVING REDUCED FLAVOR SCALPING PROPERTIES SWIMC LLC (US) 2022-11-09 EP disclosed
EP-3484964-B1 LATEX COATING COMPOSITION HAVING REDUCED FLAVOR SCALPING PROPERTIES SWIMC LLC (US) 2022-04-13 EP disclosed
US-20070232554-A1 3,6-Bridged 9,12-oxolides ENATA PHARMACEUTICALS, INC. 2007-10-04 US disclosed
US-7229972-B2 Semisynthetic trimethylenedioxy-erythromycin derivatives and their use in treating bacterial infections and cystic fibrosis; preparation ENANTA PHARMACEUTICALS, INC. (US) 2007-06-12 US disclosed
US-4215175-A Non-woven fibers coated with a polymer of ethylenically unsaturated blocked aromatic diisocyanates THE B. F. GOODRICH COMPANY (US) 1980-07-29 US disclosed
US-4191833-A BLOCKED WITH PYRAZOLE, ADDITION POLYMERS THE B.F. GOODRICH COMPANY (US) 1980-03-04 US disclosed
US-4191834-A BLOCKED WITH BENZIMIDAZOLE, ADDITION POLYMERS THE B.F. GOODRICH COMPANY (US) 1980-03-04 US disclosed
US-4190582-A Ethylenically unsaturated blocked aromatic diisocyanates THE B. F. GOODRICH COMPANY (US) 1980-02-26 US disclosed
US-4189601-A ADHESIVES, BINDERS FOR NONWOVEN FABRICS THE B. F. GOODRICH COMPANY (US) 1980-02-19 US disclosed
US-4113958-A POLYMERS USEFUL AS ADHESIVES AND BINDERS THE B. F. GOODRICH COMPANY (US) 1978-09-12 US disclosed
US-4101491-A USEFUL AS BINDERS FOR NONWOVEN FIBERS THE B. F. GOODRICH COMPANY (US) 1978-07-18 US disclosed
US-4008247-A POLYMER INTERMEDIATE THE B. F. GOODRICH COMPANY (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232554-A1 3,6-Bridged 9,12-oxolides CYP2C9, CYP2C19, CYP2D6 KIF11 2606/4885ALDH1A1 353/4885SMN1; SMN2 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.