Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700629 | 0.91 | MET (0.35) | METPARP1CSNK2A1HIPK2ROCK2 | |
| SCHEMBL13700610 | 0.91 | PARP1 (0.44) | METPARP1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL13700612 | 0.88 | KDM4E (0.38) | PARP1CSNK2A2CSNK2B | |
| SCHEMBL13699420 | 0.87 | PLK1 (0.35) | METPARP1 | |
| SCHEMBL13700615 | 0.87 | NPC1 (0.41) | PKN1PKN2HPGD | |
| SCHEMBL13700617 | 0.84 | ALDH1A1 (0.39) | PARP1HPGD | |
| SCHEMBL13699491 | 0.83 | NPC1 (0.37) | HPGD | |
| SCHEMBL13700600 | 0.83 | KMT2A (0.33) | HPGD | |
| SCHEMBL13700596 | 0.83 | ACSS2 (0.36) | PARP1HPGD | |
| SCHEMBL13700627 | 0.82 | PARP1 (0.39) | PARP1CSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |