Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 4/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.44 |
| ▸ | CHRNG | P07510 | 2/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.44 |
| ▸ | CHRND | Q07001 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130840 | 0.87 | GRIA2 (0.54) | GRIA2HPGDSCHRNA1CHRNGCHRNB1 | |
| SCHEMBL25101016 | 0.87 | GRIA2 (0.54) | GRIA2HPGDSCHRNA1CHRNGCHRNB1 | |
| SCHEMBL13768442 | 0.84 | HSP90AB1 (0.44) | ALDH1A1CYP3A4 | |
| SCHEMBL25888572 | 0.84 | NLRP3 (0.57) | GRIA2CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL25100771 | 0.84 | NLRP3 (0.57) | GRIA2CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL15179166 | 0.84 | CTSB (0.48) | ALDH1A1CTSL | |
| SCHEMBL14942915 | 0.83 | PNMT (0.51) | ALDH1A1CTSL | |
| SCHEMBL16574567 | 0.83 | CTSB (0.48) | ALDH1A1CYP1A2HIF1ASLC7A5 | |
| SCHEMBL24711924 | 0.83 | SLC1A1 (0.49) | ALDH1A1 | |
| SCHEMBL14898396 | 0.83 | PNMT (0.51) | ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221598-A1 | Use of Sanglifehrin in HCV | LIN KAI | 2009-09-03 | — | — | US | disclosed |
| US-20090221598-A1 | Use of Sanglifehrin in HCV | LIN KAI | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221598-A1 | Use of Sanglifehrin in HCV | HAVCR2, HCCS, HSP90B1 | GRIA2 4786/4885HPGDS 1138/4885CHRNA1 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.