SCHEMBL13699440

SCHEMBL13699440

Cc1cc(CCO)cc(-n2nc3ccc(C(=O)O)cc3n2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37
SELE P16581 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HCAR3 P49019 5/20 0.36
HSD17B10 Q99714 2/20 0.35
MYC P01106 1/20 0.35
ESR1 P03372 1/20 0.35
ALOX15 P16050 1/20 0.35
PTPN7 P35236 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699478 0.90 KMT2A (0.39) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700411 0.88 CYP4A11 (0.44) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700408 0.88 CA12 (0.41) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13699437 0.86 MAPT (0.46) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700414 0.86 MAPT (0.38) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700455 0.85 RARG (0.36) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700416 0.85 ACE2 (0.36) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700473 0.85 ALDH1A1 (0.36) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13700496 0.83 ALDH1A1 (0.40) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL30240966 0.82 NPC1 (0.50) ALDH1A1HPGDKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed