Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 10/20 | 0.35 |
| ▸ | JAK1 | P23458 | 10/20 | 0.35 |
| ▸ | TYK2 | P29597 | 10/20 | 0.35 |
| ▸ | JAK3 | P52333 | 10/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699440 | 0.90 | ALDH1A1 (0.39) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13700408 | 0.87 | CA12 (0.41) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13700411 | 0.87 | CYP4A11 (0.44) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL13700463 | 0.86 | GAA (0.37) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13700424 | 0.86 | JAK2 (0.33) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13699492 | 0.85 | ERN1 (0.37) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13700414 | 0.85 | MAPT (0.38) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13699457 | 0.84 | KDM4E (0.39) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13699437 | 0.83 | MAPT (0.46) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13699450 | 0.82 | KMT2A (0.41) | KMT2AMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |