SCHEMBL13699492

SCHEMBL13699492

NC(=O)c1ccc2nn(-c3cc(CCO)cc(C=O)c3O)nc2c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 9/20 0.37
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
POLB P06746 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
JAK2 O60674 6/20 0.32
JAK1 P23458 6/20 0.32
TYK2 P29597 6/20 0.32
JAK3 P52333 6/20 0.32
KMT2A Q03164 1/20 0.32
NAMPT P43490 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700473 0.90 ALDH1A1 (0.36) ERN1KDM4EALDH1A1HPGDLMNA
SCHEMBL13700465 0.86 CYP4A11 (0.43) ERN1KDM4EALDH1A1HPGDLMNA
SCHEMBL13699478 0.85 KMT2A (0.39) KDM4EALDH1A1HPGDLMNAMAPT
SCHEMBL13700467 0.85 ALDH1A1 (0.41) ERN1KDM4EALDH1A1HPGDLMNA
SCHEMBL13699498 0.85 KDM4E (0.43) ERN1KDM4EALDH1A1HPGDLMNA
SCHEMBL13699412 0.84 MAPT (0.37) ERN1KDM4EALDH1A1HPGDLMNA
SCHEMBL13700533 0.84 TYR (0.38) KDM4EALDH1A1HPGDLMNAMAPT
SCHEMBL13700483 0.84 MEN1 (0.39) KDM4EALDH1A1HPGDLMNAMAPT
SCHEMBL13700470 0.83 MAPT (0.46) KDM4EALDH1A1HPGDLMNAMAPT
SCHEMBL13700471 0.83 ERN1 (0.36) ERN1KDM4EALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2103445-B1 Heat resistance improver and reversible thermosensitive recording medium RICOH CO LTD (JP) 2015-05-06 EP disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed