SCHEMBL13699501

SCHEMBL13699501

O=Cc1cc(CCO)cc(-n2nc3cc(Cl)c(Cl)cc3n2)c1O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CDK1 P06493 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700471 0.89 ERN1 (0.36) ERN1NPC1RAB9AKDM4EALDH1A1
SCHEMBL13699498 0.86 KDM4E (0.43) ERN1NPC1RAB9AKDM4EALDH1A1
SCHEMBL13700462 0.83 RORC (0.37) ERN1NPC1RAB9AKDM4EALDH1A1
SCHEMBL13700473 0.82 ALDH1A1 (0.36) ERN1NPC1RAB9AKDM4EALDH1A1
SCHEMBL13699492 0.81 ERN1 (0.37) ERN1KDM4EALDH1A1POLBHPGD
SCHEMBL13700459 0.81 POLB (0.35) ERN1KDM4EALDH1A1POLBHPGD
SCHEMBL13700474 0.81 MEN1 (0.48) ERN1ALDH1A1POLB
SCHEMBL13699500 0.81 KDM4E (0.47) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700725 0.80 NPC1 (0.37) NPC1RAB9AKDM4EALDH1A1POLB
SCHEMBL13700402 0.80 NPC1 (0.43) NPC1RAB9AKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed