SCHEMBL13699503

SCHEMBL13699503

N#Cc1cc(CCO)cc(-n2nc3ccc(C(=O)Nc4ccccc4)cc3n2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
HPGD P15428 6/20 0.44
MAPT P10636 6/20 0.44
POLB P06746 5/20 0.44
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
KDM4E B2RXH2 6/20 0.40
HSD17B10 Q99714 5/20 0.40
MAPK1 P28482 4/20 0.40
ALOX15 P16050 2/20 0.40
KMT2A Q03164 6/20 0.39
MEN1 O00255 5/20 0.39
LMNA P02545 3/20 0.39
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39
ESR1 P03372 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700496 0.87 ALDH1A1 (0.40) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13699458 0.86 KDM4E (0.37) ALDH1A1HPGDMAPTPOLBKDM4E
SCHEMBL13699437 0.85 MAPT (0.46) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13700470 0.85 MAPT (0.46) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13699457 0.84 KDM4E (0.39) ALDH1A1HPGDMAPTPOLBKDM4E
SCHEMBL13700502 0.83 CYP4A11 (0.41) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13700466 0.83 ALDH1A1 (0.44) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13700445 0.83 LMNA (0.45) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13700488 0.82 KDM4E (0.54) ALDH1A1HPGDMAPTPOLBRAB9A
SCHEMBL13700405 0.82 ALDH1A1 (0.49) ALDH1A1HPGDMAPTPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2103445-B1 Heat resistance improver and reversible thermosensitive recording medium RICOH CO LTD (JP) 2015-05-06 EP disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed