Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19083895 | 1.00 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL19083892 | 1.00 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL3457922 | 0.89 | L3MBTL3 (0.61) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL6843039 | 0.84 | OPRM1 (0.53) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| Ammonia Solution, Strong SCHEMBL29274480 | 0.82 | OPRM1 (0.52) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL5745248 | 0.80 | OPRL1 (0.51) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL5746042 | 0.80 | OPRL1 (0.51) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL19075614 | 0.79 | DPP4 (0.52) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL19075528 | 0.79 | DPP4 (0.52) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 | |
| SCHEMBL18762175 | 0.78 | SIGMAR1 (0.43) | L3MBTL3L3MBTL1OPRL1OPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240066-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| US-7569599-B2 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20070117988-A1 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117988-A1 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | RAP1A, RHOA, MGMT | L3MBTL3 2636/4885L3MBTL1 3585/4885OPRL1 2680/4885 |
| US-20090240066-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | RAP1A, RHOA, MGMT | L3MBTL3 2636/4885L3MBTL1 3585/4885OPRL1 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.