Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.54 |
| ▸ | YAP1 | P46937 | 1/20 | 0.54 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.54 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699791 | 0.90 | KDM4E (0.66) | HPGDPOLBPKMKDM4ETEAD1 | |
| SCHEMBL13699841 | 0.84 | KDM4E (0.58) | HPGDPOLBPKMKDM4ETEAD1 | |
| SCHEMBL1852546 | 0.82 | KDM4E (0.72) | HPGDPOLBPKMKDM4ETEAD1 | |
| SCHEMBL13699837 | 0.81 | KDM4E (0.61) | HPGDPOLBPKMKDM4ETEAD1 | |
| SCHEMBL13699982 | 0.81 | POLB (0.65) | HPGDPOLBPKMKDM4ETEAD1 | |
| SCHEMBL4251178 | 0.80 | ALDH1A1 (0.72) | HPGDPOLBKDM4ETEAD1YAP1 | |
| SCHEMBL13699981 | 0.80 | POLB (0.64) | HPGDPOLBPKMKDM4ETEAD1 | |
| SCHEMBL13699835 | 0.78 | KDM4E (0.70) | HPGDPOLBKDM4ETEAD1YAP1 | |
| SCHEMBL4254445 | 0.77 | HSD17B10 (0.72) | HPGDKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL4250076 | 0.77 | KDM4E (1.00) | HPGDPOLBPKMKDM4ETEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | ADORA2A, ADORA2B, HTR1F | HPGD 3251/4885POLB 2255/4885PKM 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.