Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.52 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699996 | 0.81 | TEAD1 (0.52) | KMT2AKDM4EMEN1TEAD1YAP1 | |
| SCHEMBL13699978 | 0.77 | POLB (0.65) | KMT2AKDM4EMEN1TEAD1YAP1 | |
| SCHEMBL13699984 | 0.76 | POLB (0.64) | KMT2AKDM4EMEN1TEAD1YAP1 | |
| SCHEMBL13700021 | 0.75 | ALDH1A1 (0.52) | KMT2AKDM4EMEN1TEAD1YAP1 | |
| SCHEMBL13700000 | 0.72 | MAPT (0.51) | KMT2AKDM4EMEN1TEAD1YAP1 | |
| SCHEMBL13700083 | 0.72 | MEN1 (0.53) | KMT2AKDM4EMEN1MAPTATM | |
| SCHEMBL13700035 | 0.72 | KMT2A (0.53) | KMT2AKDM4EMEN1MAPTATM | |
| SCHEMBL20659877 | 0.71 | TEAD1 (0.75) | KMT2AKDM4EMEN1TEAD1YAP1 | |
| SCHEMBL13699846 | 0.71 | KDM4E (0.61) | KMT2AKDM4EMEN1MAPTTP53 | |
| SCHEMBL13699958 | 0.70 | MEN1 (0.57) | KMT2AKDM4EMEN1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | ADORA2A, ADORA2B, HTR1F | KMT2A 2861/4885KDM4E 4227/4885MEN1 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.