Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700392 | 0.89 | NPC1 (0.47) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL77763 | 0.84 | LMNA (0.58) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL29517159 | 0.84 | LMNA (0.58) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL7566832 | 0.84 | MAPT (0.42) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL13700700 | 0.84 | KDM4E (0.43) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL9408806 | 0.83 | NPC1 (0.66) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL13700399 | 0.83 | CA12 (0.48) | NPC1RAB9ALMNAMAPTKDM4E | |
| SCHEMBL13700406 | 0.83 | MAPT (0.39) | NPC1RAB9ALMNAMAPTKDM4E | |
| Hydrogen Sulfide SCHEMBL8439446 | 0.83 | LMNA (0.56) | NPC1RAB9ALMNAMAPTKDM4E | |
| Ammonia Solution, Strong SCHEMBL8437470 | 0.83 | LMNA (0.56) | NPC1RAB9ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |