Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.33 |
| ▸ | JAK1 | P23458 | 6/20 | 0.33 |
| ▸ | TYK2 | P29597 | 6/20 | 0.33 |
| ▸ | JAK3 | P52333 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700416 | 0.90 | ACE2 (0.36) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13700438 | 0.88 | CYP4A11 (0.42) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13700440 | 0.87 | CYP4F2 (0.38) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13700442 | 0.86 | HSP90AA1 (0.37) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13699478 | 0.86 | KMT2A (0.39) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL13700445 | 0.84 | LMNA (0.45) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13700463 | 0.83 | GAA (0.37) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13699492 | 0.83 | ERN1 (0.37) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL13700443 | 0.82 | NPC1 (0.37) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL13700410 | 0.82 | KDM4E (0.35) | KDM4EALDH1A1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |