Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699378 | 0.85 | PKM (0.36) | KDM4EPKMALDH1A1POLBHPGD | |
| SCHEMBL5666244 | 0.85 | GCGR (0.35) | KDM4EPKMALDH1A1POLBPDE2A | |
| SCHEMBL2637886 | 0.83 | ALDH1A1 (0.35) | KDM4EPKMALDH1A1POLBHPGD | |
| SCHEMBL13700724 | 0.83 | KDM4E (0.35) | KDM4EPKMALDH1A1POLBHPGD | |
| SCHEMBL13700443 | 0.83 | NPC1 (0.37) | KDM4EGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL13700410 | 0.83 | KDM4E (0.35) | KDM4EGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL5666240 | 0.82 | PTPN5 (0.37) | KDM4EALDH1A1POLBHPGDALOX15 | |
| SCHEMBL13700459 | 0.81 | POLB (0.35) | KDM4EPKMALDH1A1POLBHPGD | |
| SCHEMBL13700416 | 0.80 | ACE2 (0.36) | KDM4EGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL13699510 | 0.80 | KDM4E (0.40) | KDM4EPKMALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |