SCHEMBL13699510

SCHEMBL13699510

N#Cc1cc(CCO)cc(-n2nc3ccc(C(F)(F)F)cc3n2)c1O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PKM P14618 1/20 0.32
AR P10275 1/20 0.32
CTSK P43235 1/20 0.31
KCNH2 Q12809 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.30
CACNA1H O95180 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700488 0.84 KDM4E (0.54) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700724 0.83 KDM4E (0.35) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13699378 0.83 PKM (0.36) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13699467 0.83 KDM4E (0.42) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700495 0.82 ALDH1A1 (0.43) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL2637886 0.81 ALDH1A1 (0.35) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700459 0.81 POLB (0.35) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700496 0.80 ALDH1A1 (0.40) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700441 0.80 KDM4E (0.33) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13699454 0.80 KDM4E (0.40) KDM4EALDH1A1POLBHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed