Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699455 | 0.87 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13700706 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13700488 | 0.86 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13699467 | 0.85 | KDM4E (0.42) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13700499 | 0.84 | HSD17B10 (0.41) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13700406 | 0.83 | MAPT (0.39) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13700502 | 0.83 | CYP4A11 (0.41) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13700496 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13699510 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EHPGDMAPK1POLB | |
| SCHEMBL13699454 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EHPGDMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |