⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201803 | 0.82 | — | — | |
| SCHEMBL4196957 | 0.77 | — | — | |
| SCHEMBL514546 | 0.77 | — | — | |
| SCHEMBL11368310 | 0.75 | — | — | |
| SCHEMBL5965396 | 0.75 | — | — | |
| SCHEMBL835510 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL536268 | 0.72 | LMNA (0.38) | — | |
| SCHEMBL955673 | 0.72 | LMNA (0.38) | — | |
| SCHEMBL953592 | 0.72 | LMNA (0.38) | — | |
| SCHEMBL465609 | 0.72 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158446-A1 | CYCLIC COMPOUND HAVING SELECTIVE INHIBITORY ACTION ON KRAS OVER HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-16 | — | — | US | claimed |
| EP-4309741-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-01-24 | — | — | EP | claimed |
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | claimed |
| CN-117247359-A | Dendrimer-like lipid compound, liposome, lipid complex, lipid nanoparticle and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-19 | — | — | CN | claimed |
| WO-2023236824-A1 | DENDRON-LIKE LIPID COMPOUND, LIPOSOME, LIPID COMPLEX, AND LIPID NANOPARTICLE AND USE THEREOF | 中国科学院广州生物医药与健康研究院 | 2023-12-14 | — | — | WO | claimed |
| CN-117062800-A | Aryl sulfide and preparation method and application thereof | 山东康乔生物科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116143833-A | Preparation method of phosphorus imide catalyst and application of phosphorus imide catalyst in Saucy-Marbet rearrangement reaction | 万华化学集团股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| US-20230026641-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-01-26 | — | — | US | claimed |
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | claimed |
| CN-114630835-A | Process for the preparation of peptide compounds comprising sterically bulky amino acids | 中外制药株式会社 | 2022-06-14 | — | — | CN | claimed |
| US-RE36617-E | Anastrozole and salts as anticancer agent | ZENECA LIMITED (GB) | 2000-03-14 | — | — | US | claimed |
| EP-0659729-B1 | Process for preparing chlorides of polyfluorochloro- and perfluoro carboxylic acids in the presence of chlorine | SOLVAY FLUOR & DERIVATE (DE) | 1998-06-24 | — | — | EP | claimed |
| EP-0838458-A1 | NOVEL REAGENT FOR TETRAZOLE SYNTHESIS AND PROCESS FOR PRODUCING TETRAZOLES THEREWITH | CHUGOKU KAYAKU KABUSHIKI KAISHA (JP) | 1998-04-29 | — | — | EP | claimed |
| EP-0483850-B1 | Process for producing salts of fluorinated alcohols | AUSIMONT SPA (IT) | 1995-08-09 | — | — | EP | claimed |
| EP-0296749-B1 | (Substituted aralkyl) heterocyclic compounds | ZENECA LTD (GB) | 1994-10-26 | — | — | EP | claimed |
| EP-0260713-B1 | PROCESS FOR THE PREPARATION OF PERFLUOROACYL FLUORIDES | AUSIMONT S.p.A. (IT) | 1991-03-06 | — | — | EP | claimed |
| US-4935437-A | (Substituted aralkyl) heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-19 | — | — | US | claimed |
| EP-0296749-A1 | (Substituted aralkyl) heterocyclic compounds | ZENECA LIMITED (GB) | 1988-12-28 | — | — | EP | claimed |
| US-4787930-A | 5-amino-1-phenyl-pyrazole herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-29 | — | — | US | claimed |
| EP-0235558-A2 | 5-Amino-1-phenyl pyrazoles | BAYER AG (DE) | 1987-09-09 | — | — | EP | claimed |