SCHEMBL835510

SCHEMBL835510

O=[C]C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL957653 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL955673 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL465609 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL536268 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL957475 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL953592 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL956942 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL6656018 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL7782669 0.97 LMNA (0.38) LMNATHRBCA2
SCHEMBL7779858 0.97 LMNA (0.38) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143833-A Preparation method of phosphorus imide catalyst and application of phosphorus imide catalyst in Saucy-Marbet rearrangement reaction 万华化学集团股份有限公司 2023-05-23 CN claimed
CN-118139839-A Process for producing fluorinated polyether 株式会社力森诺科 2024-06-04 CN disclosed
CN-118055920-A Process for producing fluorinated polyether 株式会社力森诺科 2024-05-17 CN disclosed
US-20230398096-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-12-14 US disclosed
CN-116143833-A Preparation method of phosphorus imide catalyst and application of phosphorus imide catalyst in Saucy-Marbet rearrangement reaction 万华化学集团股份有限公司 2023-05-23 CN disclosed
US-20230142119-A1 TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-05-11 US disclosed
US-20220306578-A1 TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-09-29 US disclosed
CN-113621388-A Compounds and compositions 住友化学株式会社 2021-11-09 CN disclosed
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
US-10961456-B2 Dichroic dye compound, polarizing film, and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-30 US disclosed
US-4716232-A 1-(vinyl phosphonate adduct) pyrazolidinones ELI LILLY AND COMPANY (US) 1987-12-29 US disclosed
EP-0203722-A1 Bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-12-03 EP disclosed
EP-0203723-A1 2,3-(dihydro)bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-12-03 EP disclosed
EP-0202794-A1 7-Substituted-2,3-(Dihydro) bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-11-26 EP disclosed
EP-0202046-A1 7-Substituted bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-11-20 EP disclosed
US-4108631-A HERBICIDES, INSECTICIDES ELI LILLY AND COMPANY (US) 1978-08-22 US disclosed
US-RE29508-E HERBICIDES AND INSECTICIDES ELI LILLY AND COMPANY (US) 1978-01-03 US disclosed
US-4011341-A HERBICIDES ELI LILLY AND COMPANY (US) 1977-03-08 US disclosed
US-3989840-A Control of animal parasites with ring-substituted N-(2,2-difluoroalkanoyl)-O-phenylenediamines ELI LILLY AND COMPANY (US) 1976-11-02 US disclosed
US-3962263-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142119-A1 TETRACYCLIC COMPOUND ALK, TTR, ACVR1 LMNA 2777/4885THRB 300/4885CA2 291/4885
US-20220306578-A1 TETRACYCLIC COMPOUND ALK, TTR, ACVR1 LMNA 2777/4885THRB 300/4885CA2 291/4885
US-20230398096-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND ALK, ALPI, TTR LMNA 2928/4885THRB 685/4885CA2 940/4885
US-10961456-B2 Dichroic dye compound, polarizing film, and uses thereof CRY1, C5, C9 LMNA 424/4885THRB 3567/4885CA2 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.