SCHEMBL536268

SCHEMBL536268

O=[C]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL957653 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL7779858 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL955673 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL7782669 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL957475 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL6656018 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL953592 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL956942 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL465609 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL835510 0.97 LMNA (0.33) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117244061-A Mesoporous silica coated gold nanorod non-viral vector 德州学院 2023-12-19 CN claimed
CN-113416336-A Fluorine-containing end group active hydroxyl friction-resistant high-shear-resistant composite rubber material 四川大学 2021-09-21 CN claimed
CN-107446546-B Novel magnetic sealing material and preparation method thereof 四川理工学院 2020-08-25 CN claimed
CN-106630838-B A kind of building decoration engineering water-repellent paint 广东久巴新材料科技有限公司 2019-02-12 CN claimed
CN-107446546-A A kind of novel magnetic encapsulant and preparation method thereof 四川理工学院 2017-12-08 CN claimed
EP-1482932-B1 N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS ARRAY BIOPHARMA INC (US) 2009-11-25 EP claimed
US-20070167421-A1 Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides ITO MASHITO 2007-07-19 US claimed
EP-1718305-A1 PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES Bayer CropScience AG (DE) 2006-11-08 EP claimed
WO-2005079798-A1 PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES BAYER CROPSCIENCE AG (DE) 2005-09-01 WO claimed
EP-1075461-B1 PERFLUORINATED ESTERS OF ALKANOYL L-CARNITINE FOR THE PREPARATION OF CATIONIC LIPIDS FOR THE INTRACELLULAR DELIVERY OF PHARMACOLOGICALLY ACTIVE COMPOUNDS SIGMA TAU IND FARMACEUTI (IT) 2004-07-28 EP claimed
US-6476243-B1 Perfluorinated esters of alkanoyl L-carnitine for the preparation of cationic lipids for the intracellular delivery of pharmacologically active compounds SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2002-11-05 US claimed
US-6468713-B1 FILTER FOR PLASMA DISPLAY, A SECRET INK; PHTHALOCYANINE COMPOUND HAVING AN ACYL OR AROYL GROUP INTRODUCED ONTO THE NITROGEN ATOM ON EACH BENZOTHIAZINE RING OF THE PHTHALOCYANINE NUCLEUS; REACTION WITH ANHYDRIDE YAMAMOTO CHEMICALS, INC. (JP) 2002-10-22 US claimed
WO-1996008524-A1 WATER-BORNE FUNCTIONALISED POLYMERS STAHL INTERNATIONAL B.V. (NL) 1996-03-21 WO claimed
US-20240200022-A1 METHODS AND SYSTEMS FOR THE CULTURE OF CELLS AT LIQUID-LIQUID INTERFACES UNIV LONDON QUEEN MARY (GB) 2024-06-20 US disclosed
CN-118139839-A Process for producing fluorinated polyether 株式会社力森诺科 2024-06-04 CN disclosed
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN disclosed
US-4011341-A HERBICIDES ELI LILLY AND COMPANY (US) 1977-03-08 US disclosed
US-4008047-A FLUOROACYLATED ETHYL CELLULOSE NORTH STAR RESEARCH INSTITUTE (US) 1977-02-15 US disclosed
US-3989840-A Control of animal parasites with ring-substituted N-(2,2-difluoroalkanoyl)-O-phenylenediamines ELI LILLY AND COMPANY (US) 1976-11-02 US disclosed
US-3962263-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167421-A1 Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides DPYD, DHFR, TYMP LMNA 4712/4885THRB 3187/4885CA2 3752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.