Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.51 |
| ▸ | WNT3A | P56704 | 5/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020481 | 0.82 | HTR1B (0.63) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL30164255 | 0.81 | HTR1B (0.61) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL14880251 | 0.80 | HTR1B (0.56) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL12597509 | 0.79 | CTNNB1 (0.55) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL3492979 | 0.79 | CTNNB1 (0.56) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL3494527 | 0.78 | HTR1B (0.58) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL14137372 | 0.77 | MEN1 (0.59) | NAMPTMEN1KMT2AMAPT | |
| SCHEMBL103953 | 0.76 | CTNNB1 (0.59) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL28431104 | 0.76 | CTNNB1 (0.59) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL826046 | 0.76 | HTR1B (0.59) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | HTR1B 2098/4885TAS1R3 3911/4885TAS1R1 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.