Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.56 |
| ▸ | WNT3A | P56704 | 8/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.51 |
| ▸ | HTR3A | P46098 | 3/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880251 | 0.84 | HTR1B (0.56) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL12020481 | 0.83 | HTR1B (0.63) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL1922479 | 0.82 | TAS1R3 (0.58) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| Hydrochloric Acid SCHEMBL30164255 | 0.81 | HTR1B (0.61) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL3441414 | 0.80 | AR (0.61) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL3494527 | 0.79 | HTR1B (0.58) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL13701657 | 0.79 | HTR1B (0.55) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL29987426 | 0.78 | CTNNB1 (0.63) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL4318315 | 0.78 | CTNNB1 (0.58) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B | |
| SCHEMBL663873 | 0.78 | CTNNB1 (0.63) | CTNNB1WNT3ATAS1R3TAS1R1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492378-B2 | GSK-3β inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20100069381-A1 | GSK-3BETAINHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
| WO-2009071577-A1 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071577-A1 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | GSK3B, GSK3A, GSKIP | CTNNB1 6/4885WNT3A 31/4885TAS1R3 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.