Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.51 |
| ▸ | WNT3A | P56704 | 7/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020481 | 0.82 | HTR1B (0.63) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL30164255 | 0.81 | HTR1B (0.61) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL14880251 | 0.80 | HTR1B (0.56) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL103953 | 0.80 | CTNNB1 (0.59) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL28431104 | 0.80 | CTNNB1 (0.59) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL3492979 | 0.79 | CTNNB1 (0.56) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL13701657 | 0.78 | HTR1B (0.55) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL16617148 | 0.76 | CTNNB1 (0.54) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL826046 | 0.76 | HTR1B (0.59) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A | |
| SCHEMBL1922479 | 0.75 | TAS1R3 (0.58) | HTR1BTAS1R3TAS1R1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492378-B2 | GSK-3β inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20100069381-A1 | GSK-3BETAINHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | GSK3B, GSK3A, GSKIP | HTR1B 2902/4885TAS1R3 4420/4885TAS1R1 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.