Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16544497 | 0.91 | UTS2R (0.41) | KCNA5KCNH2AGTR1MEN1NPC1 | |
| SCHEMBL28232057 | 0.83 | DNM1 (0.42) | KCNA5KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28220432 | 0.81 | DNM1 (0.46) | KCNA5KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4723984 | 0.80 | MAPT (0.41) | AGTR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL26296867 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2HCAR3HTTMAP3K5 | |
| SCHEMBL1554369 | 0.78 | MAPT (0.39) | KCNA5KMT2AMAPTCYP2D6KCNE1 | |
| SCHEMBL9272657 | 0.77 | KCNA5 (0.42) | KCNA5KCNH2AGTR1MEN1NPC1 | |
| SCHEMBL12874146 | 0.77 | CRHR1 (0.40) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL16316871 | 0.77 | CRHR1 (0.44) | KCNA5KCNH2MAPTSMN1; SMN2CYP2D6 | |
| SCHEMBL6446263 | 0.75 | CYP2D6 (0.53) | KCNA5KCNH2AGTR1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006078-A | Gonadotropin releasing hormone receptor antagonists | WYETH CORP (US) | 2007-07-25 | — | — | CN | claimed |
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | claimed |
| US-20090226411-A1 | CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS | AVENTIS PHARMA S.A. (FR) | 2009-09-10 | — | — | US | disclosed |
| CN-101006078-A | Gonadotropin releasing hormone receptor antagonists | WYETH CORP (US) | 2007-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226411-A1 | CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS | DPYD, NTPCR, NME1 | KCNA5 4647/4885KCNH2 4642/4885AGTR1 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.