Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707186 | 0.88 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9265040 | 0.88 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL14748632 | 0.84 | SMYD3 (0.74) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL19445791 | 0.83 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL17916120 | 0.83 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL23384768 | 0.82 | SMYD3 (0.76) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL26407281 | 0.81 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL21249304 | 0.81 | LMNA (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL7233864 | 0.81 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL3771488 | 0.81 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | RAB9A 2708/4885NPC1 1477/4885SMN1; SMN2 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.