Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468916 | 0.81 | MAPT (0.49) | MAPTTDP1HTTL3MBTL1POLB | |
| SCHEMBL16634491 | 0.78 | TGM2 (0.51) | LIPEHTTALDH1A1CYP2C19 | |
| SCHEMBL30952875 | 0.77 | NPC1 (0.48) | MAPTLIPETDP1L3MBTL1POLB | |
| SCHEMBL30952876 | 0.77 | NPC1 (0.48) | MAPTLIPETDP1L3MBTL1POLB | |
| SCHEMBL1533800 | 0.77 | NPC1 (0.48) | MAPTLIPETDP1L3MBTL1POLB | |
| SCHEMBL15938678 | 0.76 | HDAC1 (0.56) | MAPTTDP1L3MBTL1POLBHDAC1 | |
| SCHEMBL25970594 | 0.74 | JAK3 (0.42) | MAPTTDP1HTTL3MBTL1POLB | |
| SCHEMBL29951306 | 0.73 | KCNQ4 (0.46) | LIPEHTTPOLBRXFP1SMN1; SMN2 | |
| SCHEMBL7779085 | 0.72 | TDP1 (0.68) | MAPTTDP1GAAJAK3KDM4E | |
| SCHEMBL22200946 | 0.71 | XDH (0.46) | MAPTTDP1HTTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664909-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | Smart Holograms Limited (GB) | 2006-06-07 | — | — | EP | claimed |
| WO-2005031442-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | SMART HOLOGRAMS LIMITED (GB) | 2005-04-07 | — | — | WO | claimed |
| EP-2522679-B1 | PHENYLBORONIC ACID MONOMER AND PHENYLBORONIC ACID POLYMER | NAT INST FOR MATERIALS SCIENCE (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-8241574-B2 | Ophthalmic device comprising a holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2012-08-14 | — | — | US | disclosed |
| US-20110286064-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | BURLES BARRY (GB) | 2011-11-24 | — | — | US | disclosed |
| US-7998412-B2 | Ophthalmic device comprising a holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |
| US-20090021697-A1 | Ophthalmic Device Comprising a Holographic Sensor | SMART HOLOGRAMS LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
| EP-1664909-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | Smart Holograms Limited (GB) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005031442-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | SMART HOLOGRAMS LIMITED (GB) | 2005-04-07 | — | — | WO | disclosed |