Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702398 | 0.88 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MEN1CYP3A4TSHR | |
| SCHEMBL13702340 | 0.87 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MEN1CYP3A4TSHR | |
| SCHEMBL14007204 | 0.87 | HRH3 (0.58) | ALDH1A1SMN1; SMN2HRH3KDM4EPOLB | |
| SCHEMBL13701823 | 0.85 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1CYP3A4TSHR | |
| SCHEMBL14007196 | 0.81 | HRH3 (0.47) | ALDH1A1SMN1; SMN2HRH3MEN1TSHR | |
| SCHEMBL13702173 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TSHRKMT2AKDM4E | |
| SCHEMBL13702178 | 0.78 | HRH3 (0.51) | ALDH1A1SMN1; SMN2HRH3TSHRCYP2C19 | |
| SCHEMBL13702164 | 0.78 | HRH3 (0.48) | ALDH1A1SMN1; SMN2HRH3CYP3A4TSHR | |
| SCHEMBL13702184 | 0.77 | HRH3 (0.50) | ALDH1A1SMN1; SMN2HRH3MEN1TSHR | |
| SCHEMBL13702165 | 0.77 | BRD4 (0.49) | ALDH1A1SMN1; SMN2CYP2C19KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | ALDH1A1 376/4885SMN1; SMN2 4398/4885HRH3 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.