Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702171 | 0.90 | POLB (0.51) | HRH3KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13702164 | 0.89 | HRH3 (0.48) | HRH3KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13702308 | 0.85 | ALDH1A1 (0.49) | KMT2APOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14007204 | 0.84 | HRH3 (0.58) | HRH3POLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL13701815 | 0.84 | MEN1 (0.44) | KMT2ASMN1; SMN2ALDH1A1GAARXFP1 | |
| SCHEMBL13702182 | 0.81 | ALDH1A1 (0.57) | HRH3KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4249071 | 0.81 | GAA (0.49) | KMT2APOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14034428 | 0.80 | GAA (0.46) | KMT2APOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL13702178 | 0.78 | HRH3 (0.51) | HRH3POLBSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL14007252 | 0.78 | EPHX2 (0.56) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | ELDRUP ANNE BETTINA | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | EPHX1, EPHX2, DOHH | HRH3 114/4885KMT2A 3400/4885POLB 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.