Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13704125 | 0.88 | MEN1 (0.39) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL4296733 | 0.86 | MEN1 (0.40) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704077 | 0.86 | MEN1 (0.41) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704083 | 0.83 | MEN1 (0.47) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL4293357 | 0.81 | MEN1 (0.40) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704079 | 0.80 | MEN1 (0.44) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704073 | 0.79 | MEN1 (0.47) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704059 | 0.79 | MEN1 (0.48) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704076 | 0.77 | MEN1 (0.47) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL13704071 | 0.77 | MEN1 (0.46) | MEN1KMT2AKDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | BONFANTI JEAN-FRANCOIS | 2009-09-03 | — | — | US | disclosed |
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | BONFANTI JEAN-FRANCOIS | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | GABRA5, GABRA4, GABRA3 | MEN1 4829/4885KMT2A 1440/4885KDM4E 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.