SCHEMBL1370518

SCHEMBL1370518

CCOC(=O)c1ccc2[nH]nnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.52
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 4/20 0.51
RAB9A P51151 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MAPT P10636 1/20 0.51
HSD17B10 Q99714 4/20 0.50
HPGD P15428 3/20 0.50
MAPK1 P28482 3/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
POLB P06746 2/20 0.50
HRH3 Q9Y5N1 1/20 0.50
MMP2 P08253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21221672 0.89 ALDH1A1 (0.49) HCRTR1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL452867 0.88 PKN1 (0.53) HCRTR1ALDH1A1KDM4ERAB9AMEN1
SCHEMBL29278218 0.86 ESR1 (0.51) ALDH1A1KDM4ERAB9AMEN1KMT2A
SCHEMBL6217917 0.86 HRH3 (0.50) HCRTR1ALDH1A1KDM4ERAB9AMEN1
SCHEMBL8468092 0.84 ALDH1A1 (0.52) ALDH1A1RAB9AMAPTESR1NPC1
SCHEMBL29278219 0.84 ALDH1A1 (0.52) ALDH1A1RAB9AMAPTESR1NPC1
SCHEMBL13516553 0.83 ALDH1A1 (0.44) HCRTR1ALDH1A1KDM4ERAB9AMEN1
SCHEMBL1155736 0.83 CREBBP (0.47) ALDH1A1KDM4ERAB9AMEN1KMT2A
SCHEMBL13411771 0.82 CYP2D6 (0.42) HCRTR1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL9473892 0.82 SNCA (0.46) HCRTR1ALDH1A1KDM4ERAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118272797-A Environment-friendly passivation solution for antioxidant and corrosion-resistant copper foil, preparation and application thereof, and passivation method for copper foil 江西理工大学 2024-07-02 CN claimed
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US disclosed
CN-118272797-A Environment-friendly passivation solution for antioxidant and corrosion-resistant copper foil, preparation and application thereof, and passivation method for copper foil 江西理工大学 2024-07-02 CN disclosed
EP-3856654-B1 DUAL SPRAY PATTERN NOZZLES ICP CONSTRUCTION INC (US) 2024-04-24 EP disclosed
US-11850610-B2 Non-linear spray pattern nozzles ICP CONSTRUCTION, INC. (US) 2023-12-26 US disclosed
US-11738359-B2 Foam dispensing gun with third stream ICP CONSTRUCTION, INC. (US) 2023-08-29 US disclosed
US-11730566-B2 Device for storage and application and method VOCO GMBH (DE) 2023-08-22 US disclosed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
US-11603484-B2 Process for seaming of artificial turf using low-pressure adhesives ICP CONSTRUCTION, INC. (US) 2023-03-14 US disclosed
WO-2022116998-A1 FUSED HETEROCYCLIC DERIVATIVES AS HBV INHIBITORS Janssen Sciences Ireland Unlimited Company (IE) 2022-06-09 WO disclosed
EP-1230906-B1 Thermochromic dental material IVOCLAR VIVADENT AG (LI) 2004-09-22 EP disclosed
US-20040127507-A1 Imidazolidine compounds MILLENNIUM PHARMACEUTICALS, INC. (US) 2004-07-01 US disclosed
US-20040122026-A1 Imidazolidine compounds MILLENNIUM PHARMACEUTICALS, INC. 2004-06-24 US disclosed
US-6670436-B2 When using tooth-coloured fixing materials for the cementing of tooth-coloured restorations IVOCLAR VIVADENT AG (LI) 2003-12-30 US disclosed
US-20030225288-A1 Imidazolidine compounds MILLENNIUM PHARMACEUTICALS, INC. 2003-12-04 US disclosed
WO-2003087063-A1 IMIDAZOLIDINE COMPOUNDS AS CHEMOKINE RECEPTOR MODULATORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-10-23 WO disclosed
EP-1272827-A1 ANALYTE DETECTION & APPARATUS THEREFOR UNIVERSITY OF STRATHCLYDE (GB) 2003-01-08 EP disclosed
US-20020152929-A1 Thermochromic dental material IVOCLAR VIVADENT AG. 2002-10-24 US disclosed
WO-2001077650-A1 ANALYTE DETECTION & APPARATUS THEREFOR UNIVERSITY OF STRATHCLYDE (GB) 2001-10-18 WO disclosed
US-4957949-A Thermochromic color masterbatch MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127507-A1 Imidazolidine compounds IRAK1, IRAK4, IRAK2 HCRTR1 3389/4885ALDH1A1 569/4885KDM4E 4423/4885
US-20030225288-A1 Imidazolidine compounds IRAK1, IRAK4, IRAK2 HCRTR1 3389/4885ALDH1A1 569/4885KDM4E 4423/4885
US-11730566-B2 Device for storage and application and method TAS2R10, LSM12, CASP10 HCRTR1 4508/4885ALDH1A1 2024/4885KDM4E 2830/4885
US-20040122026-A1 Imidazolidine compounds IRAK1, IRAK4, IRAK2 HCRTR1 3389/4885ALDH1A1 569/4885KDM4E 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.