Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705493 | 0.86 | ALDH1A1 (0.45) | ALDH1A1ALOX12HPGDMAPTKMT2A | |
| SCHEMBL13705499 | 0.81 | KMT2A (0.44) | ALDH1A1ALOX12HPGDMAPTKMT2A | |
| SCHEMBL13705486 | 0.78 | KDM4E (0.47) | ALDH1A1HPGDMAPTKMT2AGAA | |
| SCHEMBL13705592 | 0.76 | MGLL (0.45) | ALDH1A1ALOX12HPGDMAPTKMT2A | |
| SCHEMBL13705494 | 0.72 | AKR1C3 (0.42) | ALDH1A1MAPTKMT2AHTTLMNA | |
| SCHEMBL11370080 | 0.70 | GAA (0.49) | ALDH1A1HPGDMAPTKMT2AGAA | |
| SCHEMBL13705496 | 0.68 | MAPT (0.38) | ALDH1A1ALOX12HPGDMAPTKMT2A | |
| SCHEMBL8404715 | 0.67 | L3MBTL1 (0.67) | ALDH1A1MAPTKMT2AGAAMGLL | |
| SCHEMBL10494615 | 0.65 | MGLL (0.52) | ALDH1A1MAPTKMT2AGAAMGLL | |
| SCHEMBL30026877 | 0.65 | ALDH1A1 (0.54) | ALDH1A1ALOX12HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |