Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 6/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052440 | 0.78 | CYP3A4 (0.48) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27438340 | 0.68 | KCNQ3 (0.41) | KMT2AMEN1ALDH1A1LMNAKCNQ3 | |
| SCHEMBL13705490 | 0.68 | ALDH1A1 (0.54) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL12182424 | 0.67 | ALDH1A1 (0.57) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27313063 | 0.65 | KCNQ3 (0.43) | ALDH1A1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7662714 | 0.65 | RRM2 (0.44) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4442545 | 0.64 | ADRA2A (0.49) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL27928111 | 0.63 | KCNQ3 (0.41) | ALDH1A1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7663627 | 0.63 | ALDH1A1 (0.50) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7663631 | 0.63 | ALDH1A1 (0.50) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |