Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 7/20 | 0.34 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.31 |
| ▸ | GJB2 | P29033 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520392 | 1.00 | IGF2R (0.34) | IGF2RITPR3ITPR1TLR4LY96 | |
| SCHEMBL26029373 | 0.90 | LY96 (0.34) | IGF2RTLR4LY96 | |
| SCHEMBL21202642 | 0.89 | IGF2R (0.31) | IGF2RGJB2 | |
| SCHEMBL10005839 | 0.88 | ITPR3 (0.30) | ITPR3ITPR1 | |
| SCHEMBL19608814 | 0.88 | ITPR3 (0.30) | ITPR3ITPR1 | |
| SCHEMBL1642428 | 0.88 | ITPR3 (0.30) | ITPR3ITPR1 | |
| SCHEMBL13706079 | 0.85 | TLR4 (0.31) | TLR4LY96 | |
| SCHEMBL26029385 | 0.85 | TLR4 (0.31) | TLR4LY96 | |
| SCHEMBL19768566 | 0.80 | IGF2R (0.35) | IGF2R | |
| SCHEMBL8059872 | 0.79 | LGALS8 (0.34) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004352-B1 | OLIGONUCLEOTIDE MODULATORS OF B-CELL CLL/LYMPHOMA 11A (BCL11A) AND USES THEREOF | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2017-09-27 | — | — | EP | disclosed |