Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CHKA | P35790 | 4/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310810 | 0.91 | TSHR (0.44) | TSHRCHKALTA4HNR1I2ALDH1A1 | |
| SCHEMBL439584 | 0.82 | TSHR (0.59) | TSHRLTA4HNR1I2ALDH1A1MEN1 | |
| SCHEMBL5937231 | 0.82 | CHKA (0.55) | CHKANR3C2ALDH1A1MEN1KMT2A | |
| SCHEMBL14488604 | 0.82 | TSHR (0.59) | TSHRLTA4HNR1I2ALDH1A1MEN1 | |
| SCHEMBL14174076 | 0.82 | TSHR (0.59) | TSHRLTA4HNR1I2ALDH1A1MEN1 | |
| SCHEMBL279125 | 0.82 | TSHR (0.59) | TSHRLTA4HNR1I2ALDH1A1MEN1 | |
| Alcohol SCHEMBL11357181 | 0.81 | CHKA (0.48) | TSHRCHKANR3C2ALDH1A1MEN1 | |
| SCHEMBL7155149 | 0.81 | NR3C2 (0.56) | TSHRCHKANR3C2ALDH1A1MEN1 | |
| SCHEMBL18873551 | 0.80 | TSHR (0.56) | TSHRCHKALTA4HNR3C2ALDH1A1 | |
| SCHEMBL13462904 | 0.80 | CHKA (0.58) | TSHRCHKANR3C2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589081-B2 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA AG (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | HDHD5, PNP, PHOSPHO1 | TSHR 3705/4885CHKA 1713/4885LTA4H 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.