Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 8/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706380 | 0.91 | TSHR (0.54) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL19278352 | 0.85 | AOC3 (0.46) | ALDH1A1LTA4HCA12CA1CA2 | |
| SCHEMBL165131 | 0.84 | ALDH1A1 (0.64) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL27418407 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL22682027 | 0.80 | RXRA (0.49) | — | |
| SCHEMBL15014122 | 0.78 | ADRA2A (0.50) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL308282 | 0.78 | TSHR (0.48) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL18843564 | 0.77 | PPARG (0.39) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL13645979 | 0.77 | MAPT (0.41) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL32670482 | 0.77 | TSHR (0.38) | TSHRALDH1A1CYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4172858-A | Flame-resistant polymer compositions | CIBA-GEIGY AG (CH) | 1979-10-30 | — | — | US | disclosed |
| US-4163731-A | HYDRAULIC FLUIDS | CIBA-GEIGY AG (CH) | 1979-08-07 | — | — | US | disclosed |