Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13707148 | 0.78 | CYP1A2 (0.44) | NOS1NOS3NOS2CYP1A2HRH4 | |
| SCHEMBL4367124 | 0.69 | NOS1 (0.42) | NOS1NOS3NOS2CYP1A2HRH4 | |
| SCHEMBL7565143 | 0.68 | NOS3 (0.61) | NOS1NOS3NOS2CYP1A2HRH4 | |
| SCHEMBL2790028 | 0.65 | NOS3 (0.61) | NOS1NOS3NOS2CYP1A2HRH4 | |
| SCHEMBL29389936 | 0.62 | — | — | |
| Bromide SCHEMBL31738696 | 0.61 | PPARD (0.47) | NOS1NOS3NOS2CYP1A2HRH4 | |
| SCHEMBL23377992 | 0.60 | PKM (0.31) | — | |
| SCHEMBL14086322 | 0.60 | CA12 (0.40) | — | |
| SCHEMBL29390642 | 0.59 | — | — | |
| SCHEMBL9193111 | 0.58 | CYP1A2 (0.71) | NOS1NOS3NOS2CYP1A2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592297-B2 | Anti-friction anti-wear lubricant additive | CATERPILLAR INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-20080103073-A1 | Anti-friction anti-wear lubricant additive | CATERPILLAR INC. | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103073-A1 | Anti-friction anti-wear lubricant additive | SSB, F12, F10 | NOS1 1289/4885NOS3 1223/4885NOS2 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.