Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372731 | 1.00 | DRD2 (0.55) | DRD2DRD3OPRK1ESR1ESR2 | |
| SCHEMBL1370800 | 1.00 | DRD2 (0.55) | DRD2DRD3OPRK1ESR1ESR2 | |
| SCHEMBL5970080 | 1.00 | DRD2 (0.55) | DRD2DRD3OPRK1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL28150626 | 0.98 | DRD2 (0.53) | DRD2DRD3OPRK1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL5969925 | 0.98 | DRD2 (0.53) | DRD2DRD3OPRK1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL5969965 | 0.98 | DRD2 (0.53) | DRD2DRD3OPRK1ESR1ESR2 | |
| Sulfuric Acid SCHEMBL28237715 | 0.91 | DRD2 (0.47) | DRD2DRD3OPRK1ESR1ESR2 | |
| SCHEMBL2803692 | 0.89 | ACHE (0.51) | DRD2DRD3OPRK1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2807478 | 0.87 | ACHE (0.50) | DRD2DRD3OPRK1ESR1ESR2 | |
| SCHEMBL32665589 | 0.84 | DRD2 (0.55) | DRD2DRD3OPRK1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105177103-B | A kind of preparation method of R-6- hydroxyl -1- aminoidan | 陈永军 | 2019-03-12 | — | — | CN | claimed |
| CN-105087742-B | Dynamic Kinetic Resolution prepares R-6- hydroxyl -1- aminoidans | 陈永军 | 2018-09-14 | — | — | CN | claimed |
| CN-105017035-B | Method for preparing (S)-6-hydroxy-1-aminoindane through dynamic kinetic resolution | 山东省立医院 | 2017-05-24 | — | — | CN | claimed |
| CN-105177103-A | Preparation method for R-6-hydroxy-1-aminoindan | CHEN YONGJUN | 2015-12-23 | — | — | CN | claimed |
| CN-105175273-A | Method for preparing S-6-hydroxy-1-aminoindane | WU LING | 2015-12-23 | — | — | CN | claimed |
| CN-105087742-A | Method for preparing R-6-hydroxy-1-aminoindane through dynamic kinetic resolution | CHEN YONGJUN | 2015-11-25 | — | — | CN | claimed |
| CN-105017035-A | Method for preparing (S)-6-hydroxy-1-aminoindane through dynamic kinetic resolution | CHEN YONGJUN | 2015-11-04 | — | — | CN | claimed |
| CN-105002257-A | Preparation method of S-6-hydroxyl-1-aminoindane | CHEN YONGJUN | 2015-10-28 | — | — | CN | claimed |
| JP-4782252-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| EP-0738149-B1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 2006-11-29 | — | — | EP | claimed |
| US-6528685-B2 | Such as (R)-N-(2-acetamido)-1-aminoindan for treatment of Parkinson's disease, dementia, epilepsy, convulsions, or seizures | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2003-03-04 | — | — | US | claimed |
| US-20020068839-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING 1-AMINOINDAN AND DERIVATIVES THEREOF AND PROCESS FOR PREPARING OPTICALLY ACTIVE 1-AMINOINDAN DERIVATIVES | COHEN SASSON (IL) | 2002-06-06 | — | — | US | claimed |
| US-5994408-A | THERAPY FOR PARKINSON'S DISEASE; ANTICONVULSANT | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1999-11-30 | — | — | US | claimed |
| EP-0738149-A4 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 1999-10-27 | — | — | EP | claimed |
| EP-0738149-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | claimed |
| EP-3143002-B1 | COMPOUNDS WITH NEURAL PROTECTIVE EFFECT, AND PREPARATION AND USE THEREOF | GUANGZHOU MAGPIE PHARMACEUTICAL CO LTD (CN) | 2020-12-02 | — | — | EP | disclosed |
| CN-105177103-B | A kind of preparation method of R-6- hydroxyl -1- aminoidan | 陈永军 | 2019-03-12 | — | — | CN | disclosed |
| WO-1996021640-A1 | OPTICALLY ACTIVE AMINOINDANE DERIVATIVES AND PREPARATION THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-07-18 | — | — | WO | disclosed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068839-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING 1-AMINOINDAN AND DERIVATIVES THEREOF AND PROCESS FOR PREPARING OPTICALLY ACTIVE 1-AMINOINDAN DERIVATIVES | PARK7, GAP43, PSEN1 | DRD2 211/4885DRD3 223/4885OPRK1 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.